Faculty Commons, A Center for Teaching, Learning, Scholarship and Service coordinates all professional development, grants and assessment activities of faculty at New York City College of Technology. Faculty Commons adopts a programmatic approach to professional development and operates as a faculty resource and think tank where members collaborate on a variety of projects to shape curriculum, pedagogy and assessment.
The Office of Sponsored Programs (OSP) helps faculty and administrators compete for and win grants that strengthen the intellectual climate and improve the learning environment at City Tech. The office provides notices of grant opportunities and works with faculty and administrators over the life-cycle of a grant – from concept development through close-out.
The Professional Activity Report and Self-Evaluation (PARSE) is the documentation of a faculty member’s accomplishments during each academic year and cumulatively, in the three principal areas of teaching, scholarly and professional growth, and service. The PARSE serves as the basis for the annual evaluation. It is also provides faculty with an instrument to present to departmental and college review committees for reappointment, tenure, and promotion.
Abstract: Cardiotoxicity is unfortunately a common side effect of many modern chemotherapeutic agents. The mechanisms that underlie these detrimental effects on heart muscle, however, remain unclear. The Drug Toxicity Signature Generation Center at ISMMS aims to address this unresolved issue by providing a bridge between molecular changes in cells and the prediction of pathophysiological effects. I will discuss ongoing work in which we use next-generation sequencing to quantify changes in gene expression that occur in cardiac myocytes after they are treated with potentially toxic chemotherapeutic agents. I will focus in particular on the computational pipeline we are developing that integrates sophisticated sequence alignment, statistical and network analysis, and dynamical mathematical models to develop novel predictions about the mechanisms underlying drug-induced cardiotoxicity.
Jaehee Shim is a Ph.D candidate in the Biophysics and Systems Pharmacology Program at Icahn School of Medicine at Mount Sinai (ISMMS). As a part of her Ph.D. studies, she is building dynamical prediction models based on analysis of gene expression data generated by the Drug Toxicity Signature Generation Center at ISMMS. She received her B.S in Biochemistry from the University of Michigan-Dearborn. Prior to starting her Ph.D, Jaehee worked at the ISMMS Genomics Core with a team of senior scientists and gained experience in improving and troubleshooting RNA sequencing protocols using Next Generation Sequencing Platforms.